THE INFLUENCE OF PSEUDOMONAS-AERUGINOSA ON LIPOSOMES

The interaction of liposomes loaded with Ponceau red (used as a marker ) with Pseudomonas aeruginosa cells was observed and it resulted in ma rker leakage. The marker leakage from liposomes was low in physiologic al fluids. The interaction was independent of secreted phospholipase C level and the serotype of the tested strain. Six of 37 examined isola tes did not cause any release of the marker from the liposomes. Marker release of over 50% of total encapsulated material was observed only for ten of the strains tested.