Ae. Turco et al., AN ITALIAN FAMILY WITH AUTOSOMAL-DOMINANT POLYCYSTIC KIDNEY-DISEASE UNLINKED TO EITHER THE PKD1 OR PKD2 GENE, American journal of kidney diseases, 28(5), 1996, pp. 759-761
We describe a family with autosomal dominant polycystic kidney disease
in which molecular typing with closely linked markers for the PKD1 an
d PKD2 genes indicated absence of linkage. Thus, a third stilt unknown
locus appears likely to be involved in disease development. This is t
he fourth ''PKD3-linked'' family described to date and the first from
Italy. (C) 1996 by the National Kidney Foundation, Inc.