Y. Wakisaka et al., TANDEM OPERATION OF A TURBO BLOOD PUMP (BP-80-TYPE CENTRIFUGAL PUMP) TO REDUCE HEMOLYSIS, Artificial organs, 20(6), 1996, pp. 572-574
When operating turbo blood pumps in tandem, the strength of shear stre
ss is reduced, but the exposure duration of the stress is increased. T
he purpose of this experiment was to compare the degree of contributio
n of these two factors on hemolysis as well as to evaluate the effecti
veness of the tandem operation of turbo blood pumps. Tandem operation
of two Bio-pumps (BP-80; Medtronics Bio-medicus, Inc., Eden Prairie, M
innesota, U.S.A.) were compared with single operation of a BP-80 in in
vitro hemolysis tests in three different driving conditions, that is,
pumping heads of 200, 350, and 500 mm Hg under a pump flow rate of 5
L/min. The Allen's hemolytic indexes of the tandem operation at pumpin
g heads of 200, 350, and 500 mm Hg were 0.014, 0.020, and 0.080 mg/dl,
respectively. The hemolytic indexes of the single operation at pumpin
g heads of 200, 350, and 500 mm Hg were 0.014, 0.056, and 0.12 mg/dl,
respectively. These results indicate that tandem operation is a useful
method of reducing hemolysis with the BP-80 under high pumping heads
and that the effect on hemolysis of exposure to higher shear stresses
may be more serious than that of longer durations of exposure to shear
stress in turbo blood pumps.