PAIRED RECORDINGS FROM NEURONS

Paired recording is a powerful and versatile tool to examine communica tion between and within neurones. This technique has provided new insi ghts in studies of synaptic function and plasticity, of neuronal integ ration, and of the decoding of neuronal circuits. Recent studies using dual recordings in combination with morphology have successfully dete rmined the number of transmitter release sites between synaptically co nnected neurones. Important progress in understanding the dynamics of signal transmission within individual cells has been made possible usi ng infra-red microscopy, which permits dual recordings from visualized somatic and dendritic sites on a single neurone.