RESPIRATORY CONTROL INDEX OF MITOCHONDRIA ISOLATED FROM REGENERATING RAT-LIVER

Authors
SVATKOVA R CERVINKOVA Z KALOUS M RAUCHOVA H DRAHOTA Z
Citation
R. Svatkova et al., RESPIRATORY CONTROL INDEX OF MITOCHONDRIA ISOLATED FROM REGENERATING RAT-LIVER, Physiological Research, 45(3), 1996, pp. 249-252
Citations number
20
Categorie Soggetti
Physiology
Journal title
Physiological Research → ACNP
ISSN journal
08628408
Volume
45
Issue
3
Year of publication
1996
Pages
249 - 252
Database
ISI
SICI code
0862-8408(1996)45:3<249:RCIOMI>2.0.ZU;2-#
Abstract
Mitochondria were isolated from regenerating rat liver 12, 24 and 48 h after partial hepatectomy. The ''State 3'' and ''State 4'' respiratio n were measured in the presence of succinate. The P/O quotient and res piratory control index (RCI) were calculated. The experimental data sh owed that the partial uncoupling of oxidative phosphorylation in regen erating liver mitochondria occurring in the early period of regenerati on is partly due to free fatty acids.