We develop a transformation theory in quantum physics, where the trans
formation operators, defined in the infinite-dimensional Hilbert space
, have right-unitary inverses only. Through several theorems, we discu
ss the properties of state space of such operators. As one application
of the right-unitary transformation (RUT), we show that using the RUT
method, we can solve exactly various interactions of many-level atoms
with quantized radiation fields, where the energy of atoms can be two
levels, three levels in Lambda, V, and = configurations, and up to hi
gher (> 3) levels. These interactions have wide applications in atomic
physics, quantum optics, and quantum electronics. In this paper, we f
ocus on two typical systems: one is a two-level generalized Jaynes-Cum
mings model, where the cavity field varies with the external source; t
he other one is the interaction of a three-level atom with quantized r
adiation fields, where the atoms have n-configuration energy levels, a
nd the radiation fields are one-mode or two-mode cavities.