PICROLIV PROTECTS AGAINST ALCOHOL-INDUCED CHRONIC HEPATOTOXICITY IN RATS

Authors
RASTOGI R SAKSENA S GARG NK KAPOOR NK AGARWAL DP DHAWAN BN
Citation
R. Rastogi et al., PICROLIV PROTECTS AGAINST ALCOHOL-INDUCED CHRONIC HEPATOTOXICITY IN RATS, Planta medica, 62(3), 1996, pp. 283-285
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
Planta medica → ACNP
ISSN journal
00320943
Volume
62
Issue
3
Year of publication
1996
Pages
283 - 285
Database
ISI
SICI code
0032-0943(1996)62:3<283:PPAACH>2.0.ZU;2-I
Abstract
Daily administration of ethyl alcohol (3.76 g/kg, p.o.) for 45 days re sulted in significant changes in several biochemical parameters of the liver and serum of albino rats. After exposure to alcohol for 30 days when Picroliv (12 mg/kg, p.o.), an iridoid glycoside fraction of Picr orhiza kurroa, was administered for 15 days along with alcohol, the de gree of change in most of the parameters was reduced.