TREATMENT OF LOCALLY ADVANCED, BASAL-CELL CARCINOMA (BCC) BY NEOADJUVANT CHEMOTHERAPY AND RADIOTHERAPY

BCC is usually controlled by surgery or radiation therapy [1, 2]. Thes e treatments are not always effective or possible when the lesions are extensive (inoperable lesions, maiming surgery, dosimetric problems i n radiotherapy, unacceptable cosmetic or functional results...). Furth ermore, the tumor size is an important factor in the potential for loc al control [2]. Recent studies indicate promising results in using che motherapy as a sole and neoadjuvant treatment of advanced BCC [3, 4]. We report two cases of locally advanced BCC treated by a combination o f chemotherapy and radiotherapy.