LATE-ONSET OF ISOLATED CENTRAL-NERVOUS-SYSTEM METASTASIS OF LIPOSARCOMA - A CASE-REPORT

Metastatic soft-tissue sarcoma of the central nervous system (CNS) is exceedingly rare. We report a case of a 56-year-old male treated for a right lower extremity liposarcoma at the age of 30 years, whose first recurrence was an intracerebral metastasis occurring 26 years after r esection of the primary tumor. Initial treatment of the metastasis wit h surgical resection and adjuvant radiotherapy was followed rapidly by CNS recurrence in 3 months. Further debulking and interstitial brachy therapy were unsuccessful in controlling disease progression. Clinical presentation and treatment of brain metastases in soft-tissue sarcoma are discussed.