SYNDROME OF INAPPROPRIATE SECRETION OF ANTIDIURETIC-HORMONE IN ELDERLY PATIENTS WITH RHEUMATOID-ARTHRITIS ASSOCIATED WITH INFECTIONS - REPORT OF 2 CASES

Two rheumatoid arthritis (RA) patients with the syndrome of inappropri ate secretion of antidiuretic hormone (SIADH) during the course of inf ection are herein reported. One patient developed SIADH during the cou rse of a localized cutaneous herpes tester infection while the other d eveloped SIADH in conjunction with Staphylococcus simulans septicemia, We consider that the development of SIADH was strongly associated wit h superimposed infections in the underlying RA. This is the first repo rt discussing the association of SIADH and infections in RA patients i n which SIADH is diagnosed by measurement of plasma ADH.