All factors which govern blood now are of varying significance in vivo
, depending on the size of the vessels. The deformability of individua
l cells becomes important in the capillaries when cell diameters are s
imilar to capillary diameters. A variety of techniques have been used
to measure cell deformability, one of tile most commonly used is that
of filtration. This paper reviews the progression of filtration studie
s nifh respect to the circulatory disorder of peripheral vascular dise
ase.