COEXISTENCE OF FAMILIAL ANTIPHOSPHOLIPID SYNDROME AND FACTOR-V LEIDEN- IMPACT ON THROMBOTIC DIATHESIS

Authors
BRENNER B VULFSONS SL LANIR N NAHIR M
Citation
B. Brenner et al., COEXISTENCE OF FAMILIAL ANTIPHOSPHOLIPID SYNDROME AND FACTOR-V LEIDEN- IMPACT ON THROMBOTIC DIATHESIS, British Journal of Haematology, 94(1), 1996, pp. 166-167
Citations number
12
Categorie Soggetti
Hematology
Journal title
British Journal of Haematology → ACNP
ISSN journal
00071048
Volume
94
Issue
1
Year of publication
1996
Pages
166 - 167
Database
ISI
SICI code
0007-1048(1996)94:1<166:COFASA>2.0.ZU;2-I
Abstract
Two young siblings who presented with an unusual recurrent severe thro mboembolic phenomenon were found to have familial anti-phospholipid sy ndrome and were heterozygous for the factor V R506Q mutation, The coex istence of hereditary and acquired APC-resistance may explain the seve rity of thrombo-embolism.