ENZYMATIC PREPARATION OF OPTICALLY-ACTIVE PRECURSORS OF CPI, THE DNA ALKYLATION SUBUNIT OF THE NATURALLY-OCCURRING ANTITUMOR ANTIBIOTIC CC-1065

Authors
LING L LOWN JW
Citation
L. Ling et Jw. Lown, ENZYMATIC PREPARATION OF OPTICALLY-ACTIVE PRECURSORS OF CPI, THE DNA ALKYLATION SUBUNIT OF THE NATURALLY-OCCURRING ANTITUMOR ANTIBIOTIC CC-1065, Chemical communications, (13), 1996, pp. 1559-1560
Citations number
27
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
13
Year of publication
1996
Pages
1559 - 1560
Database
ISI
SICI code
1359-7345(1996):13<1559:EPOOPO>2.0.ZU;2-8
Abstract
Some immediate precursors of CPI, the DNA alkylation subunit of CC-106 5 are subjected to enzymatic resolution with Lipase PS in vinyl acetat e; racemic 3 is effectively resolved by two consecutive enzymatic reac tions.