CAN PHYSICAL-ACTIVITY MINIMIZE WEIGHT-GAIN IN WOMEN AFTER SMOKING CESSATION

Objectives. The purpose of this study was to examine prospectively whe ther exercise can modify weight gain after smoking cessationin women. Methods. Data were analyzed from a 2-year follow-up period (1986-1988) in the Nurses' Health Study, an ongoing cohort of 121 700 US women ag ed 40 to 75 in 1986. Results. The average weight gain over 2 years was 3.0 kg in the 1474 women who stopped smoking, and 0.6 kg among the 78 32 women who continued smoking. Among women smoking 1 to 24 cigarettes per day, those who quit without changing their levels of exercise gai ned an average of 2.3 kg more (95% confidence interval [CI] = 1.9, 2.6 ) than women who continued smoking. Women who quit and increased exerc ise by between 8 to 16 MET-hours (the work metabolic rate divided by t he resting metabolic rate) per week gained 1.8 kg (95% CI = 1.0, 2.5), and the excess weight gain was only 1.3 kg (95% CI = 0.7, 1.9) in wom en who increased exercise by more than 16 MET-hours per week. Conclusi ons. Smoking cessation is associated with a net excess weight gain of about 2.4 kg in middle-aged women. However, this weight gain is minimi zed if smoking cessation is accompanied by a moderate increase in the level of physical activity.