DETERMINATION OF THE FORMATION CONSTANT FOR THE INCLUSION COMPLEX OF METHYL-BETA-CYCLODEXTRIN WITH ANTICOAGULANT DRUGS WARFARIN AND 8-CHLOROWARFARIN IN AQUEOUS-SOLUTION

Authors
MAUPAS B LETELLIER S GUYON F
Citation
B. Maupas et al., DETERMINATION OF THE FORMATION CONSTANT FOR THE INCLUSION COMPLEX OF METHYL-BETA-CYCLODEXTRIN WITH ANTICOAGULANT DRUGS WARFARIN AND 8-CHLOROWARFARIN IN AQUEOUS-SOLUTION, Journal of inclusion phenomena and molecular recognition in chemistry, 23(4), 1995, pp. 259-267
Citations number
19
Categorie Soggetti
Chemistry,Crystallography
Journal title
Journal of inclusion phenomena and molecular recognition in chemistry → ACNP
ISSN journal
09230750
Volume
23
Issue
4
Year of publication
1995
Pages
259 - 267
Database
ISI
SICI code
0923-0750(1995)23:4<259:DOTFCF>2.0.ZU;2-V
Abstract
Inclusion of anticoagulant drugs within the cavity of methyl-beta-cycl odextrin in aqueous solution was studied by ultraviolet absorption, fl uorimetry and reversed-phase liquid chromatography. Formation constant s were obtained for complex formation of methyl-beta-cyclodextrin with warfarin and 8-chlorowarfarin.