ALKYL CAPPED CARBONATES OF BETA-CYCLODEXTRIN

The synthesis is described of alkyl capped carbonates of beta-cyclodex trin, obtained from diols activated with carbonyldiimidazole. The reac tion preferentially gave monocapped derivatives which were characteriz ed by HPLC, TLC, FT-IR and C-13-NMR. These compounds are stable at pH <7, and methyl orange was found to form stronger inclusion compounds w ith capped-beta-cyclodextrin than with the parent beta-cyclodextrin. P aramagnetic Gd(III) complexes were also studied, but they were found t o be included into capped beta-cyclodextrin as well as into beta-cyclo dextrin.