POSSIBLE SELECTIVE ELIMINATION OF RED-BLOOD-CELLS UNDER THE INFLUENCEOF COLLOIDAL SILICA

Citation
Bi. Gerashchenko et al., POSSIBLE SELECTIVE ELIMINATION OF RED-BLOOD-CELLS UNDER THE INFLUENCEOF COLLOIDAL SILICA, Medical hypotheses, 47(1), 1996, pp. 69-70
Citations number
11
Categorie Soggetti
Medicine, Research & Experimental
Journal title
ISSN journal
03069877
Volume
47
Issue
1
Year of publication
1996
Pages
69 - 70
Database
ISI
SICI code
0306-9877(1996)47:1<69:PSEORU>2.0.ZU;2-P
Abstract
The physical interaction between the red blood cells and colloidal sil ica leads to hemolysis. We propose that the nature of the red-cell eli mination as the result of this interaction is not random. As the negat ively charged silica particles at the physiological conditions electro statically react with the positive sites of the outer side of the cell membrane it seems reasonable to suppose that the cells with a low den sity of negative charges on the membrane surface area are more probabl e to be lysed in the first place.