Zuh. Mackay et Aa. Shugufta Q",mehrajuddin,"guru, HEMODILUTION IN COMPLICATED HIGH-VELOCITY - VASCULAR INJURIES OF LIMBS, Journal of Cardiovascular Surgery, 37(3), 1996, pp. 217-221
Normovolemic hemohemodilution with 3,5% polygeline was carried out in
fourteen ASA (American Society of Anesthesiologists) Class-I patients,
who had developed false aneurysms or arteriovenous fistulas following
high velocity injury on limbs. At the end of surgical procedure volum
e of mean blood drained was 1400.00+/-194.46 ml, mean surgical blood l
oss was 1665.71 (+/-33.9) ml and fluid balance was 557.14 (+/-176.40)
ml. Arteriovenous oxygen content difference (C-(a-v) O-2), central ven
ous pressure (CVP), heart rate and mean arterial pressure (MAP) did no
t show any significant variation from pre-hemorrhage value. Hematocrit
(Hct%) and hemoglobin (Hb gm%) showed a highly significant fall follo
wing hemodilution and retransfusion. However on the day of discharge H
ct% (37.5 (+/-3.88) and Hb gm% (12.84 (+/-0.82) had increased from pos
t hemodilution value of 28.96 (+/-1.98) and 10.04 (+/-0.87) respective
ly. 71% patients did not need any homologous blood transfusion. Prothr
ombin time index (PTI%) showed 7.5% fall at the conclusion of blood re
transfusion and 3.94% fall on the day of discharge. Tecnique is safe,
avoids use of homologous blood and is thus recommended during surgical
correction of complicated high velocity vascular injury of limbs.