WEGENERS GRANULOMATOSIS PRESENTING AS MAJOR SALIVARY-GLAND ENLARGEMENT

Salivary gland involvement is rare in Wegener's granulomatosis. We rep ort the first case of widespread major salivary gland enlargement as p art of the presentation of this disease. A review of the few reported cases in the literature suggests that salivary gland involvement may b e associated with a limited form of the disease and an improved progno sis. The anti-neutrophil cytoplasmic antibody (c-ANCA) assay remains t he gold standard of diagnosis but care should be exercised in the inte rpretation of results. This patient responded well to current immunosu ppressive therapy.