Purpose: Subjective and objective results were assessed after laser pr
ostatectomy with the Urolase fiber at 5 different centers in The Neth
erlands. Materials and Methods: Patients were evaluated with the inter
national prostatic symptom score questionnaire, uroflowmetry and post-
void residual volume measurements. Urodynamic investigations with pres
sure-flow analysis were performed at 2 centers. Results: Data for 233
patients were evaluated. Overall significant improvement in mean inter
national prostatic symptom score, maximum flow, post-void residual and
urodynamic parameters was noted. Differences in outcome among the cen
ters may be due to variation of technique or different selection crite
ria. Postoperative morbidity was significant, with irritative voiding
complaints for 4 to 6 weeks in up to 50% of all patients and urinary t
ract infections in 21.1%. Conclusions: Laser prostatectomy results in
subjective and objective improvement, which is operator independent. D
espite the observation that perioperative (intraoperative and immediat
e postoperative) morbidity seems less severe compared to transurethral
resection of the prostate, there is a shift toward greater postoperat
ive morbidity.