Yd. Cai et Cd. Geisler, SUPPRESSION IN AUDITORY-NERVE FIBERS OF CATS USING LOW-SIDE SUPPRESSORS .3. MODEL RESULTS, Hearing research, 96(1-2), 1996, pp. 126-140
A phenomenological model which simulates auditory-nerve (AN) two-tone
suppression was developed. The model uses the output of the outer hair
cell (OHC) to control the gain of the cochlear amplifier, which presu
mably affects only frequencies near the characteristic frequency (CF).
Among other things, the model can simulate basic AN suppression patte
rns including the 1/4 to 1/2 cycle relationships which exist between p
hase of suppression and phase of excitation to the suppressor (SUP) to
ne alone (Cai and Geisler, 1996a). Without any changes, it is also abl
e to simulate the experimental low-frequency biasing data and the supp
ression of CF component by the low-frequency SUP tone in the OHC outpu
ts (Cheatham and Dallos, 1994), These successful simulations of the su
ppression patterns support the basic assumption in the model, that the
saturation of OHC transduction current produces two-tone suppression.
However, the amplitude behavior of the model fits that obtained only
from AN fibers with high spontaneous rates (and from inner hair cells
(IHC)), but not fibers with lower spontaneous rates. It appears, there
fore, that other unknown mechanism(s) operating at stages following th
e IHC potential are important in determining the magnitude of low-side
suppression.