POLYMER-SUPPORTED SYNTHESIS OF BIOPOLYMER S - PRINCIPLES AND APPLICATIONS

The application of polymer supports for the synthesis of-polypeptides, oligonucleotides, and oligosaccharides is presented in this article a nd discussed in view of their methodology. The fundamentals of the pol ymer-supported synthesis are described as well as the role of the poly mer supports in the synthetic cycle, and the problems associated are d ebated. It is focused on typical polymer supports for each substance c lass, and an overview is given on recent tendencies of development in the polymer-supported methods of synthesis.