Wh. Vanhoutum et La. Lavery, REGIONAL VARIATION IN THE INCIDENCE OF DIABETES-RELATED AMPUTATIONS IN THE NETHERLANDS, Diabetes research and clinical practice, 31(1-3), 1996, pp. 125-132
The purpose of this study is to identify the incidence of diabetes-rel
ated lower extremity amputations in 27 health regions in the Netherlan
ds. A secondary database was used that contains all hospitalizations f
or a lower extremity amputation in the Netherlands in 1991 and 1992, r
ecorded seperately for 27 health regions. The age-adjusted incidence l
ower extremity amputations per 10 000 diabetic patients in the Netherl
ands was 25.05, and among the regions it ranged from 10.15 to 44.64. I
n the non-diabetic population, the age-adjusted incidence in the Nethe
rlands was 1.24 and ranged by region from 0.77 to 1.77. Overall, diabe
tic males had higher age-adjusted incidence rates than diabetic female
s, although in four health regions the situation was reversed. In the
Netherlands, there was an increasing incidence of diabetes-related low
er extremity amputation as age increased: < 45 years, 11.15; 45-64 yea
rs, 33.84; 65-74 years, 61.22: and 75 + years. 107.92 (P < 0.001). Thi
s continued to be a significant phenomenon for every health region (P
< 0.001). This study found a wide range in the incidence oi diabetes r
elated lower extremity amputations in the 27 health regions in the Net
herlands. A possible explanation could be differences in the severity
of diabetes, in local treatment philosophies or the availability of su
bspecialties.