Dj. Plummer et al., EFFECTIVENESS OF ENTOPTIC PERIMETRY FOR LOCATING PERIPHERAL SCOTOMAS CAUSED BY CYTOMEGALOVIRUS RETINITIS, Archives of ophthalmology, 114(7), 1996, pp. 828-831
Objective: To determine the the effectiveness of random particle motio
n, presented on a computer monitor, as a noninvasive test for detectin
g cytomegalovirus retinitis. Design: A prospective masked study in whi
ch patients were asked to trace out any disturbances on a transparency
placed over a computer monitor that displayed continuous random parti
cle motion, while the patient fixated on a central spot (entoptic peri
metry). Setting: The Acquired Immunodeficiency Syndrome Ocular Researc
h Unit at the University of California, San Diego, in La Jolla. Patien
ts: Twenty-two men with cytomegalovirus retinitis who were positive fo
r human immunodeficiency virus, II men without cytomegalovirus retinit
is who were positive for human immunodeficiency virus, and eight men w
ho were negative for human immunodeficiency virus. Intervention: None.
Measurements: Sensitivities and specificities were used to compare th
e results of entoptic perimetry with fundus photographs. Results: Ento
ptic perimetry demonstrated a 95% sensitivity and a 95% specificity in
detection of cytomegalovirus retinitis. Conclusion: Entoptic perimetr
y may be an effective and inexpensive screening test for cytomegalovir
us retinitis in hospitals and community clinics.