CYTOMEGALOVIRUS KERATITIS IN ACQUIRED-IMMUNODEFICIENCY-SYNDROME

Citation
Kr. Wilhelmus et al., CYTOMEGALOVIRUS KERATITIS IN ACQUIRED-IMMUNODEFICIENCY-SYNDROME, Archives of ophthalmology, 114(7), 1996, pp. 869-872
Citations number
29
Categorie Soggetti
Ophthalmology
Journal title
ISSN journal
00039950
Volume
114
Issue
7
Year of publication
1996
Pages
869 - 872
Database
ISI
SICI code
0003-9950(1996)114:7<869:CKIA>2.0.ZU;2-U
Abstract
A man with acquired immunodeficiency syndrome developed a generalized rash and bilateral dendritic epithelial keratitis without retinitis. C ytologic examination of superficial corneal scrapings showed many mega losyncytial giant cells that were highly characteristic of cytomegalov irus (CMV) infection. Viral cultures yielded CMV from 2 separate speci mens obtained by corneal epithelial debridement from both eyes. The sl ightly elevated, opaque, branching, nonulcerative epitheliopathy recur red after corneal scrapings and persisted despite oral and topical ant iviral therapy. Stromal keratouveitis subsequently developed. This cas e report confirms that CMV can produce corneal involvement and suggest s that CMV keratitis may be an emergent complication of acquired immun odeficiency syndrome.