A SIMIAN-VARICELLA-VIRUS (SVV) HOMOLOG TO VARICELLA-ZOSTER VIRUS GENE-21 IS EXPRESSED IN MONKEY GANGLIA LATENTLY INFECTED WITH SVV

Authors
CLARKE P MATLOCK WL BEER T GILDEN DH
Citation
P. Clarke et al., A SIMIAN-VARICELLA-VIRUS (SVV) HOMOLOG TO VARICELLA-ZOSTER VIRUS GENE-21 IS EXPRESSED IN MONKEY GANGLIA LATENTLY INFECTED WITH SVV, Journal of virology, 70(8), 1996, pp. 5711-5715
Citations number
29
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
70
Issue
8
Year of publication
1996
Pages
5711 - 5715
Database
ISI
SICI code
0022-538X(1996)70:8<5711:AS(HTV>2.0.ZU;2-A
Abstract
We have sequenced a simian varicella virus (SVV) open reading frame (O RF), 3,123 bp in length, whose product has 51% amino acid homology wit h the sequence encoded by the ORF of varicella-zoster virus gene 21, S everal regions are highly conserved between the two ORFs, with homolog ies of similar to 80%. The SW gene is transcribed in tissue culture ce lls productively infected with SW and in monkey ganglia latently infec ted with SW.