Sclerosing lymphocytic lobulitis is an inflammatory disorder of the br
east that is well recognised in women. It has only been reported previ
ously in two men; two further men with the condition are described her
e. Both presented with a breast mass, and one was an insulin dependent
diabetic. Biopsy specimens from both patients showed circumscribed pe
rivascular and, to a lesser extent, periductal collections of B and T
lymphocytes. Sclerosing lymphocytic lobulitis in the female breast sho
ws predominantly perilobular inflammation. The predominantly perivascu
lar distribution in men is consistent with the relative paucity of epi
thelium in the male breast. Interlobular fibrosis with epithelioid fib
roblasts was also present.