Purpose: Surgical exploration of the contralateral kidney in patients
with Wilms tumor is standard practice. The introduction of modern imag
ing techniques (ultrasound, computerized tomography and magnetic reson
ance imaging) in place of excretory urography has led to a more accura
te definition of intrarenal pathology. Is contralateral kidney explora
tion still necessary in patients with Wilms tumor? Materials and Metho
ds: We reviewed the records of 75 patients from 3 medical centers who
were evaluated and treated for Wilms tumor in the last 14 years. All c
hildren underwent preoperative excretory urography, computerized tomog
raphy, ultrasound and/or magnetic resonance imaging. Results: Seven bi
lateral Wilms tumors were diagnosed preoperatively and confirmed surgi
cally, whereas extensive operative exploration of the contralateral ki
dney in the other 69 patients revealed no additional pathological cond
ition. This concurred with preoperative radiological findings with 100
% sensitivity and specificity. Furthermore, 1 month to 12 years of fol
lowup (mean 4.3 years) revealed no tumor in the contralateral kidney.
The major postoperative complication was small bowel obstruction in 5
patients 15 to 180 days (mean 77.2) after explorative laparotomy. Conc
lusions: In all patients preoperative radiological investigation was a
ccurate in excluding bilaterality. With modern imaging techniques and
effective chemotherapy extensive contralateral renal exploration may n
o longer be mandatory for managing Wilms tumor.