ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY AFTER ACUTEGROUP-A STREPTOCOCCAL INFECTION

PURPOSE: We studied a case of acute posterior multifocal placoid pigme nt epitheliopathy in a 40-year-old man who had had an acute febrile il lness. METHODS: The medical record was reviewed for clinical manifesta tions, course of disease, and laboratory findings, including results o f fluorescein and indocyanine green angiography. RESULTS: The patient had the typical clinical course of acute posterior multifocal placoid pigment epitheliopathy with spontaneous resolution of posterior pole l esions and improvement in visual acuity from 20/60 to 20/20. The labor atory evaluation was remarkable for a rise in the anti-DNAse B antibod y titer between initial and convalescent-phase serum samples, providin g evidence of recent group A streptococcal infection. CONCLUSION: Alth ough acute posterior multifocal placoid pigment epitheliopathy is ofte n attributed to a postviral condition, this syndrome may also develop after an acute group A streptococcal infection.