PURPOSE: We studied a case in which a patient had unilateral retinal i
nfiltrates and a retinal vasculopathy resembling frosted branch angiit
is. He later admitted to injecting cocaine intravenously. METHODS: The
patient underwent a pars plana vitrectomy and received intravitreal a
nd intravenous amphotericin B. RESULTS: The vitreous fluid grew Fusari
um dimerium. There was rapid response to the treatment and full recove
ry of vision. CONCLUSION: Fusarium species should be considered as a p
otential pathogen in intravenous drug abusers with endogenous endophth
almitis and in patients with unilateral frosted branch angiitis.