PURPOSE: To report the presence of posterior segment neovascularizatio
n in eyes with optic nerve aplasia. METHODS: Three eyes in two patient
s with clinical optic nerve aplasia were studied. RESULTS: Examination
disclosed posterior segment neovascularization in one eye and progres
sive posterior segment neovascularization in two eyes. CONCLUSIONS: Po
sterior segment neovascularization may occur in association with optic
nerve aplasia. Retinal ischemia or retinochoroidal anatomic disorgani
zation, or both, may provide the stimulus for neovascularization in su
ch eyes.