CLONING OF THE TAG7 GENE EXPRESSED IN MET ASTATIC MOUSE-TUMORS

Authors
KUSTIKOVA OS KISELEV SL BORODULINA OR SENIN VM AFANASEVA AV KABISHEV AA
Citation
Os. Kustikova et al., CLONING OF THE TAG7 GENE EXPRESSED IN MET ASTATIC MOUSE-TUMORS, Genetika, 32(5), 1996, pp. 621-628
Citations number
23
Categorie Soggetti
Genetics & Heredity
Journal title
Genetika → ACNP
ISSN journal
00166758
Volume
32
Issue
5
Year of publication
1996
Pages
621 - 628
Database
ISI
SICI code
0016-6758(1996)32:5<621:COTTGE>2.0.ZU;2-Q
Abstract
Gene expression was compared in a metastatic (VMR-Liv) neoplastic cell line and a related nonmetastatic (VMR-O) neoplastic cell line by mean s of the differential display method. A fragment of cDNA corresponding to the tag7 gene, differentially expressed in the metastatic cell lin e, was isolated. The full-length tag7 cDNA was cloned and its nucleoti de sequence was determined. No homology between the tag7 gene and know n sequences was revealed. tag7 gene transcription was studied in some tumors, cell lines, and normal mouse organs.