FIELD-EVALUATION OF ARTHROPOD REPELLENTS, DEET AND A PIPERIDINE COMPOUND, AI3-37220, AGAINST ANOPHELES FUNESTUS AND ANOPHELES ARABIENSIS INWESTERN KENYA

A field evaluation of the repellents N,N-diethyl-3-methylbenzamide (de er) and 1-(3-cyclohexen-1-yl-carbonyl)-2-methylpiperidine (AI3-37220, a piperidine compound) was conducted against Anopheles funestus and An . arabiensis in Kenya. Both repellents provided significantly more pro tection (P < 0.001) than the ethanol control. AI3-37220 was significan tly more effective (P < 0.001) than deet in repelling both species of mosquitoes. After 9 h, 0.1 mg/cm(2) of AI3-37220 provided 89.8% and 71 .1% protection against All. arabiensis and An. funestus, respectively. Deer provided >80% protection for only 3 h, and protection rapidly de creased after this rime to 60.2% and 35.1% for An. arabiensis and An. funestus, respectively, after 9 h. Anopheles funestus was significantl y less sensitive (P < 0.001) to both repellents than An. arabiensis. T he results of this study indicate chat AI3-37220 is more effective tha n deet in repelling anopheline mosquitoes in western Kenya.