5-FLUOROURACIL-INDUCED SEVERE BUT REVERSIBLE CARDIOGENIC-SHOCK - A CASE-REPORT

5-fluorouracil cardiotoxicity is increasingly recognized with variable presentation. We report a patient who developed cardiogenic shock due to high-dose B-fluorouracil infusion (1,000 mg/m(2) every 24 hr for 9 6 hr). There was no evidence of myocardial necrosis, The patient recov ered completely without any residual cardiac dysfunction. The exact ca use of 5-fluorouracil toxicity remains to be determined. The case high lights the need for careful monitoring of patients who receive high-do se 5-fluorouracil for the development of cardiotoxicity.