COGNITIVE EFFECTS OF VIGABAKRIN - A REVIEW

Authors
Citation
F. Monaco, COGNITIVE EFFECTS OF VIGABAKRIN - A REVIEW, Neurology, 47(1), 1996, pp. 6-11
Citations number
71
Categorie Soggetti
Clinical Neurology
Journal title
ISSN journal
00283878
Volume
47
Issue
1
Year of publication
1996
Supplement
1
Pages
6 - 11
Database
ISI
SICI code
0028-3878(1996)47:1<6:CEOV-A>2.0.ZU;2-8
Abstract
Studies were reviewed in which patients who received vigabatrin underw ent cognitive testing. The overall results were categorized into five areas of cognitive function: reception, attention, intellectual functi on, memory, and psychomotor function. Overall, the studies showed eith er no detrimental effects or, in some cases, slightly improved functio n. It is speculated that a relationship exists between GABA and the re sults of these studies because vigabatrin enhances the GABAergic mecha nism in the CNS.