Studies were reviewed in which patients who received vigabatrin underw
ent cognitive testing. The overall results were categorized into five
areas of cognitive function: reception, attention, intellectual functi
on, memory, and psychomotor function. Overall, the studies showed eith
er no detrimental effects or, in some cases, slightly improved functio
n. It is speculated that a relationship exists between GABA and the re
sults of these studies because vigabatrin enhances the GABAergic mecha
nism in the CNS.