REGIONAL LOCALIZATION OF OVER 300 LOCI ON HUMAN-CHROMOSOME-22 USING ASOMATIC-CELL HYBRID MAPPING PANEL

Authors
BUDARF ML ECKMAN B MICHAUD D MCDONALD T GAVIGAN S BUETOW KH TATSUMURA Y LIU ZG HILLIARD C DRISCOLL D GOLDMUNTZ E MEESE E ZWARTHOFF EC WILLIAMS S MCDERMID H DUMANSKI JP BIEGEL J BELL CJ EMANUEL BS
Citation
Ml. Budarf et al., REGIONAL LOCALIZATION OF OVER 300 LOCI ON HUMAN-CHROMOSOME-22 USING ASOMATIC-CELL HYBRID MAPPING PANEL, Genomics, 35(2), 1996, pp. 275-288
Citations number
111
Categorie Soggetti
Genetics & Heredity
Journal title
Genomics → ACNP
ISSN journal
08887543
Volume
35
Issue
2
Year of publication
1996
Pages
275 - 288
Database
ISI
SICI code
0888-7543(1996)35:2<275:RLOO3L>2.0.ZU;2-O
Abstract
A somatic cell hybrid panel, consisting of 25 cell lines, has been dev eloped to localize loci subregionally on chromosome 22. Over 300 marke rs in the form of STSs or hybridization probes have been assigned to o ne of 24 unique regions or ''bins'' using this panel. This ordered col lection of markers will aid in the assembly of physical maps and conti gs of chromosome 22 and assist in positional cloning of disease loci m apped to chromosome 22. (C) 1996 academic Press, Inc.