Because of the increased use of the cation-anion difference (CAD) conc
ept in dry cow nutrition, many dairy nutritionists have been asking wh
ether or not CAD is important in lactation diets, Two common questions
are: (i) should CAD be monitored in rations formulated for lactating
dairy cows?; and, (2) what is the optimal CAD for high producing dairy
cows? A project was initiated to answer these questions. We combined
data from ten macromineral nutrition experiments and conducted a regre
ssion analysis, This data base contained a wide range (+5.8 to +61.2)
of dietary CAD (defined as the meg of Na + K-Cl per 10D grams of diet
DM), Regression models indicated that the optimal CAD for lactation ra
tions was between +25 and +50. Dietary CAD should be routinely monitor
ed in rations fed to high producing dairy cows, however, commercial di
ets with CAD values outside the optimal range are probably uncommon.