CASE-REPORT - ACANTHOSIS NIGRICANS IN ASSOCIATION WITH PRIMARY BILIARY-CIRRHOSIS - RESOLUTION AFTER LIVER-TRANSPLANTATION

A case is described of a 58 year old Caucasian male with primary bilia ry cirrhosis (PBC) who first presented with acanthosis nigricans of bo th axillae, skin pigmentation, which was pronounced over the posterior surface of the neck, and generalized pruritus. Following orthotopic l iver transplantation for progressive liver disease, the skin pigmentat ion, pruritus and acanthosis nigricans resolved. It is believed that t his is the first reported case of acanthosis nigricans occurring in as sociation with PBC, a phenomenon that resolved after liver transplanta tion.