KERATOSIS PALMOPLANTARIS VARIANS ET PUNCT ATA - CLINICAL VARIABILITY OF A SINGLE GENETIC-DEFECT

Palmoplantar keratodermia (PPK) varians and PPK punctata are considere d different entities within the group of hereditary palmoplantar kerat odermas, Keratosis punctata of the palmar creases constitutes a locali zed form of keratodermia palmoplantaris punctata. We describe a 31-yea r-old man exhibiting both nummular and papular keratoses on the soles, as well as small punctate keratoses confined to the palmar creases. I n view of the co-occurrence of these two types of PPK, the question ar ises whether keratosis palmoplantaris of the varians and the punctate type represent distinct entities or represent variable manifestations of the same gene defect.