The repeated association during the late Neoproterozoic Era of large c
arbon-isotopic excursions, continental glaciation, and stratigraphical
ly anomalous carbonate precipitation provides a framework for interpre
ting the reprise of these conditions on the Late Permian Earth. A pale
oceanographic model that was developed to explain these stratigraphica
lly linked phenomena suggests that the overturn of anoxic deep oceans
during the Late Permian introduced high concentrations of carbon dioxi
de into surficial environments. The predicted physiological and climat
ic consequences for marine and terrestrial organisms are in good accor
d with the observed timing and selectivity of Late Permian mass extinc
tion.