E. Frank et al., STUDY ON SHORT-TERM AND LASTING CLINICAL BENEFIT AFTER 3 YEARS OF IMMUNOTHERAPY WITH GRASSPOLLEN DEPOT ALLERGOID (ALLERGOVIT), Allergologie, 19(6), 1996, pp. 277-281
Alum-adsorbed allergoid preparations have been on the market for more
than 7 years with a short-course dosage schedule. The success of this
form of therapy, including patient compliance, has been investigated i
n a multicentre retrospective study. On the basis of data from 278 pat
ients it was shown that 85% of the patients that had completed 3 years
immunotherapy achieved a good or very good improvement. These short-t
erm results are consistent with reports from earlier controlled clinic
al trials. The lasting benefit of this causal therapy conducted in 3 c
onsecutive years was apparent in 85% of the patients an average of 3 y
ears later. Therefore, this immunotherapy can lead to good clinical im
provement and economizes on both costs and time through a reduction in
the need for antiallergic medication and the use of a short-term dosa
ge schedule.