N. Namias et al., UTILITY OF ADMISSION CHEMISTRY AND COAGULATION PROFILES IN TRAUMA PATIENTS - A REAPPRAISAL OF TRADITIONAL PRACTICE, The journal of trauma, injury, infection, and critical care, 41(1), 1996, pp. 21-25
To determine whether abnormal results of admission serum chemistry pro
files (P7: sodium (Na), potassium (K), chloride (Cl), carbon dioxide c
ontent (CO2), blood urea nitrogen (BUN), creatinine (Cr), and glucose
(GLU)), amylase (AMY), and coagulation profiles (CP: prothrombin time
(PT) and partial thromboplastin time (PTT)) in trauma patients lead to
clinical interventions, and to characterize frequency of abnormal res
ults, we prospectively gathered laboratory data on 500 consecutive pat
ients seen in our Level 1 trauma center, Clinicians were blinded to th
e study, Abnormal results were found in 93% of P7s, 7% of AMYs, and 59
% of CPs. Interventions were made for <1% of abnormal P7s, 0% of abnor
mal amylase, and 5% of patients with abnormal CP, We conclude that inf
ormation provided by routine admission chemistry and coagulation profi
les in trauma patients seldom lead to clinical interventions, These te
sts should not be ordered routinely on admission in trauma patients.