Rf. Laitano et al., EFFECTS OF NUCLEAR-INTERACTIONS ON ENERGY AND STOPPING POWER IN PROTON-BEAM DOSIMETRY, Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment, 376(3), 1996, pp. 466-476
Most experimental methods for proton beam dosimetry require stopping p
ower values and proton energy distributions in the irradiated material
s. At proton energies of interest in radiotherapy, nuclear interaction
s in biological tissue or in tissue-equivalent materials are not negli
gible. As a consequence of nuclear interactions the primary proton flu
ence is attenuated and lower energy secondary protons and other charge
d particles are generated. Whenever the proton energy has to be determ
ined along the beam path also this low-energy component should be acco
unted for. The energy spectra due to primary and secondary protons in
a tissue-equivalent material were obtained by a Monte Carlo simulation
based on the FLUKA code. The results obtained for various incident en
ergies from 60 to 300 MeV show that the proton energy spectra along th
e depth of the irradiated material can appreciably depend on the amoun
t of proton nuclear interactions. If the effect of nuclear interaction
s is not accounted, for in determining the proton energy distribution,
deviations even greater than 10% can occur in the corresponding stopp
ing powers. The consequences of this effect on absorbed dose determina
tion are discussed and quantitatively assessed in the energy range of
interest.