TRANSFORMATION OF A RACEMIC-MIXTURE BY A CHIRAL REAGENT OR CATALYST TO GIVE REGIOISOMERIC PRODUCTS

The transformation of a racemic mixture under the influence of a chira l reagent or catalyst is discussed in the case where regioisomeric pro ducts are obtained. The general relationships correlating the ee's and the quantities of the various products are given. The special case of asymmetric Baeyer-Villiger oxidation of racemic ketones is taken as a n example. Sometimes regioisomeric products are derived from opposite enantiomers, which implies that the regioselectivity of a reaction on an enantiomerically pure starting material will be controlled by the a bsolute configuration of the chiral reagent or catalyst.