GLUTAMATE-RECEPTOR SUBTYPES LOCALIZE TO PATCHES IN THE DEVELOPING STRIATUM

Citation
A. Snyderkeller et Lc. Costantini, GLUTAMATE-RECEPTOR SUBTYPES LOCALIZE TO PATCHES IN THE DEVELOPING STRIATUM, Developmental brain research, 94(2), 1996, pp. 246-250
Citations number
22
Categorie Soggetti
Neurosciences
ISSN journal
01653806
Volume
94
Issue
2
Year of publication
1996
Pages
246 - 250
Database
ISI
SICI code
0165-3806(1996)94:2<246:GSLTPI>2.0.ZU;2-U
Abstract
The distribution of glutamate receptors in the developing striatum of the rat was studied using antibodies specific to AMPA and NMDA subtype s. Immunocytochemistry revealed a greater density of GluR1, GluR2/3, N MDAR1, and NMDAR2A/2B receptors in patches that matched the patches of substance P-immunoreactive neurons and dopaminergic terminals. GluR1 immunoreactive patches were the most distinctive and were present alre ady at embryonic day 19.