Toxins are one of the inventive strategies that bacteria have develope
d in order to survive. As virulence factors, they play a major role in
the pathogenesis of infectious diseases. Recent discoveries have once
more highlighted the effectiveness of these precisely adjusted bacter
ial weapons. Furthermore, toxins have become an invaluable tool in the
investigation of fundamental cell processes, including regulation of
cellular functions by various G proteins, cytoskeletal dynamics and ne
ural transmission, In this review, the bacterial toxins are presented
in a rational classification based on the molecular mechanisms of acti
on.