In this retrospective study based on 140 esotropic and 51 exotropic pa
tients, the factors influencing successful outcome and response to str
abismus surgery were investigated, Thirteen independent variables were
chosen, The pre-operative deviation was found to be the only discrimi
nant factor for early and late successful surgical outcomes in esotrop
ic patients, For exotropic patients the visual acuity of the left eye
was the discriminant factor for early successful surgical outcome. In
esotropic patients the response to surgery increased with increasing a
mounts of pre-operative deviation, It was lower for patients with olde
r age of onset and larger amounts of medial rectus recession, For exot
ropic patients the response to surgery was higher for larger pre-opera
tive deviations. Eliminating possible sources of error when determinin
g the pre-operative deviation will improve the predictability of the r
esponse to surgery and surgical outcome.