SIMPLE AND CONDENSED BETA-LACTAMS .27. REACTION OF -(4-METHOXYPHENYL)-4-(TETRAZOL-5-YL)AZETIDIN-2-ONE AND XYPHENYL)-5-(TETRAZOL-5-YL-METHYL)PYRROLIDIN-2-ONE WITH WITH CERIUM(IV) AMMONIUM-NITRATE (CAN)
Lt. Giang et al., SIMPLE AND CONDENSED BETA-LACTAMS .27. REACTION OF -(4-METHOXYPHENYL)-4-(TETRAZOL-5-YL)AZETIDIN-2-ONE AND XYPHENYL)-5-(TETRAZOL-5-YL-METHYL)PYRROLIDIN-2-ONE WITH WITH CERIUM(IV) AMMONIUM-NITRATE (CAN), Tetrahedron, 52(30), 1996, pp. 10169-10184
Treatment of pyrrolidinone 3a with CAN under the usual conditions lead
s to formation of spiro compound 12, rather than to N-demethoxyphenyla
tion. A study of the reactions of compound 12 with sodium chloride and
sodium iodide furnished the proof for our assumption that the related
non-isolable compounds 6 and 11 are the intermediates of the anomalou
s reactions of compounds 1a and 2a, respectively, with CAN. Copyright
(C) 1996 Elsevier Science Ltd