56 cases of polyhydramnios, which were diagnosed sonographically over
a period of three years, were analysed retrospectively in this study.
In 9334 births, the prevalence of this symptom was 0.6%. Malformations
were the most common cause (26.7%) of polyhydramnios (p <0.001). In c
omparison to our normal patient group gestational diabetes, twin pregn
ancies with elevated amniotic fluid of one twin, virus infections, fet
al chromosome abnormalities were diagnosed at a significantly higher r
ate (p <0.001). The perinatal mortality rate (28.5%) in comparison to
our normal collective (1.6%) was also significantly higher. Because of
the high mortality, polyhydramnios must be assessed precisely and tre
ated if possible. Fetal karyotyping should be routinely performed in t
he second trimester.