SERUM LDH - A MARKER OF DISEASE-ACTIVITY AND ITS RESPONSE TO THERAPY IN IDIOPATHIC PULMONARY FIBROSIS

Authors
VANKRUGTEN M COBBEN NAM LAMERS RJS VANDIEIJENVISSER MP WAGENAAR SS WOUTERS EFM DRENT M
Citation
M. Vankrugten et al., SERUM LDH - A MARKER OF DISEASE-ACTIVITY AND ITS RESPONSE TO THERAPY IN IDIOPATHIC PULMONARY FIBROSIS, Netherlands journal of medicine, 48(6), 1996, pp. 220-223
Citations number
14
Categorie Soggetti
Medicine, General & Internal
Journal title
Netherlands journal of medicine → ACNP
ISSN journal
03002977
Volume
48
Issue
6
Year of publication
1996
Pages
220 - 223
Database
ISI
SICI code
0300-2977(1996)48:6<220:SL-AMO>2.0.ZU;2-6
Abstract
In the following case report the determination of serum lactate dehydr ogenase (LDH)-a simple though non-specific test -reflects changes of d isease activity and clinical improvement during treatment with cycloph osphamide and a tapered dose of prednisone from 100 to 0 mg daily in a 43-year-old woman with idiopathic pulmonary fibrosis. The trend obser ved in this case indicates that the serum LDH-activity may be directly proportional to the extent of this diffuse inflammatory pulmonary dis ease.